- Product Details
Keywords
- 59277-89-3
- acycloguanosine
- 59277-89-3
Quick Details
- ProName: acycloguanosine
- CasNo: 59277-89-3
- Molecular Formula: C8H11N5O3
- Appearance: White crystalline powder
- Application: Use broad-spectrum antivirals, includi...
- DeliveryTime: Within7-10 days after receipt of your ...
- PackAge: As customer request
- Port: Qingdao,China
- ProductionCapacity: 100 Kilogram/Month
- Purity: 98%
- Storage: Store in a cool,dry place and keep awa...
- Transportation: Common products:Sea/Air/Courier ...
- LimitNum: 100 Gram
Superiority
Details
chemical property
White crystalline powder, odorless and tasteless. It's slightly soluble in water. 256.5, melting point 257 ℃ (methanol). Acute toxicity LD50 mice (mg/kg) : > 10000 orally; 1000 abdominal injection.
melting point 256-257°C
storage condition −20°C
solubility H2O: 0.7 mg/mL
form powder
color white
Merck 146
Stable. Incompatible with strong oxidizing agents.
CAS ] 59277-89-3(CAS DataBase Reference)
quality standard
98%
- Dangerous Number
Category toxic
Toxic graded poisoning
Acute toxicity subcutaneous - rat LD50:620 mg/kg; Abdominal cavity - rat LD50:860 mg/kg
Flammable dangerous characteristics combustible; Combustion releases toxic nitrogen oxide smoke; Side effects; Allergic dermatitis, fantasy, fantasy
Storage and transportation characteristics warehouse ventilation and low temperature drying; Separate storage with food ingredients
Agent dry powder, foam, sand, carbon dioxide, fog water
Dangerous goods mark Xi
Danger type code 36/37/38
Use and storage
Use broad-spectrum antivirals, including purine nuclear compounds, in the body to convert to triphosphate compounds, interfere with viral DNA polymerase, inhibit viral DNA replication and play an antiviral role. It has a strong effect on the virus. For the prevention and treatment of viral skin or mucosal infection, it is also used for hepatitis b, herpes simplex keratitis, and zhe virus infection.
Use of antiviral drugs for herpes virus disease
The use of this product is a derivative of purine nucleoside, which has inhibitory effect on the synthesis of DNA, and its anti-herpes virus activity is 160 times stronger than that of adenosine. Clinical use of herpes simplex virus encephalitis, herpes viral keratitis and genital infection, HIV infection and cytomegalovirus infection and cytomegalovirus infection, chronic hepatitis b, etc.
The purpose is to transform the body into a triphosphate compound, which interferes with the role of the herpes simplex virus DNA polymerase and the replication of viral DNA. Alpha-dna polymerases of cells also have inhibitory effects, but to a lesser degree. Allergy to this product is not used. Patients with renal dysfunction, pregnant women, nursing women should be careful. Intravenous infusion should be slow. It is necessary to input the appropriate amount of water to avoid the accumulation of acyclovir in the renal tuguan and affect the renal function. The area under the plasma concentration curve of the product is increased by the plasma concentration of the product with a half-life and universal use. The diluted medicine should not be preserved and reused.
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