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Home > Products >  Prucalopride 99%

Prucalopride 99% CAS NO.179474-81-8

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    99.5%(10-100)Gram99.5%(101-500)Gram

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  • ProName: Prucalopride 99%
  • CasNo: 179474-81-8
  • Molecular Formula: C18H26ClN3O3
  • Appearance: white powder
  • Application: used for research
  • DeliveryTime: Within 3-7 days after receipt of your ...
  • PackAge: As customer request
  • Port: Qingdao,China
  • ProductionCapacity: 100 Metric Ton/Day
  • Purity: ≧99.5%
  • Storage: Store in a cool,dry place and keep awa...
  • Transportation: Common products:Sea/Air/Courier Dange...
  • LimitNum: 10 Gram
  • Moisture Content: 4.0~6.0%
  • Impurity: ≦0.6%
  • Single impurity: ≦0.1%
  • Methanol: Methanol

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PRODUCT NAME :Prucalopride

CAS NUMBER: 179474-81-8
Other name:
R 093877;R093877;Resolor;Unii-0A09iuw5tp;Prucalopride(R-93877)
 
Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,
including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc

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Prucalopride

PRODUCT NAME :Prucalopride
STRUCTURE
CAS NUMBER: 179474-81-8
MOLECULAR FORMULA C18H26ClN3O3
MOLECULAR WEIGHT 367.874
BATCH NO. 201711002
 
Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,
including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc
 
Mete-analysis showed that the efficacy rate was significantly higher in prucalopride(179474-81-8)group (29.2%) than in the placebo group (12.6%, RR=2.37, 95% CI 2.02-2.79, P〈0.001), while it was similar to that of PEG 3350+electrolytes group. The incidence rates of headache, dizziness, diarrhea, abdominal pain, and nausea were higher in the prucalopride group than in the placebo group (P≤ 0.05). There were no differences in the incidence of flatulence and prolonged Q T interval between the two groups (P〉0.05). Conclusion Prucalopride is effective in the treatment of CC, with relatively milder and lower incidence of adverse reaction, and it could be a new choice for the treatment of CC.
 
 

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Specification

 

Test Item                            Criteria Prescribe

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Characteristics                   White to off-white powder
Water                                  4.0~6.0%
Melting point                       100~110
Single impurity                    ≦0.1%
Purity                                  ≧99.5%
Solvent residue                   Methanol≦0.3%,   Ethyl Alcohol≦0.5% ,THF≦0.072%

 

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