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- 127243-85-0
- H-89 dihydrochloride seller in China
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Quick Details
- ProName: H-89 dihydrochloride
- CasNo: 127243-85-0
- Molecular Formula: C20H22BrCl2N3O2S
- Appearance: White solid
- Application: Pharmaceutical Intermedaite
- DeliveryTime: Within 3-7 days after receipt of your ...
- PackAge: 1g, 10g, 100g, 1kg
- Port: Shanghai china
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 98%
- Storage: Store in a cool,dry place and keep awa...
- Transportation: Common products:Sea/Air/Courier Dange...
- LimitNum: 100 Metric Ton
Superiority
Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.
Details
Details
| Product Name: | H-89 dihydrochloride |
| Synonyms: | H-89;H-89 DIHYDROCHLORIDE;H-89 HYDROCHLORIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, DIHYDROCHLORIDE;N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE;N-[2-[P-BROMOCINNAMYLAMINO]-ETHYL]-5-ISOQUINOLINESULFONMIDE |
| CAS: | 127243-85-0 |
| MF: | C20H20BrN3O2S |
| MW: | 446.36 |
| EINECS: | |
| Product Categories: | Protein Kinase Inhibitors and Activators;Inhibitor |
| Mol File: | 127243-85-0.mol |
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| H-89 dihydrochloride Chemical Properties |
| mp | 195-200°C |
| density | 1.436 |
| storage temp. | 2-8°C |
| solubility | H2O: ≥10 mg/mL |
| form | powder |
| color | off-white |
| CAS DataBase Reference | 127243-85-0(CAS DataBase Reference) |
| Safety Information |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| H-89 dihydrochloride Usage And Synthesis |
| Chemical Properties | White Solid |
| Usage | Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM |
| Biological Activity | Protein kinase A inhibitor that also inhibits several other kinases (IC 50 values are 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKB α and MAPKAP-K1b). |
| H-89 dihydrochloride Preparation Products And Raw materials |
