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Home > Products >  Dacomitinib (PF299804)

Dacomitinib (PF299804) CAS NO.1110813-31-4

  • Min.Order: 10 Gram
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Keywords

  • Dacomitinib (PF299804)
  • 99%Dacomitinib (PF299804)
  • 1110813-31-4

Quick Details

  • ProName: Dacomitinib (PF299804)
  • CasNo: 1110813-31-4
  • Molecular Formula: C24H25ClFN5O2
  • Appearance: white solid
  • Application: Dacomitinib (PF299804), which name is ...
  • DeliveryTime: Within7-10 days after receipt of your ...
  • PackAge: As customer request
  • Port: Qingdao,China
  • ProductionCapacity: 100 Kilogram/Week
  • Purity: 99%
  • Storage: room temp
  • Transportation: By Sea/Air/Courier
  • LimitNum: 10 Gram

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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

Details

Dacomitinib (PF299804)

CAS: 1110813-31-4
MF: C24H25ClFN5O2
MW: 469.9390032
Appearance: White solid
Assay:  99%
Boiling point: 665.7±55.0 °C(Predicted)
desnity: 1.344
Uses:

Dacomitinib is a selective and irreversible inhibitor of EGFR. It is a drug candidate for the treatment of non-small cell lung carcinoma.

PF299804 is a potent, irreversible pan-ErbB inhibitor against ErbB1, ErbB2 and ErbB4 with IC50 of 6 nM, 45.7 nM and 73.7 nM, respectively.

 

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