- Product Details
Keywords
- 21679-14-1 factory in China
- Fludarabine factory in China
- 21679-14-1 seller in China
Quick Details
- ProName: Fludarabine
- CasNo: 21679-14-1
- Molecular Formula: C10H12FN5O4
- Appearance: White Solid
- Application: Irreversible muscarinic agonist .DNA s...
- DeliveryTime: Within7-10 days after receipt of your ...
- PackAge: As customer request
- Port: Qingdao,China
- ProductionCapacity: 100 Kilogram/Month
- Purity: 98%
- Storage: Store in a cool,dry place and keep awa...
- Transportation: Common products:Sea/Air/Courier ...
- LimitNum: 100 Gram
- MW:: 285.23
- EINECS:: 244-525-5
- Mol File:: 21679-14-1.mol
Superiority
Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.
Details
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Fludarabine Basic information Product Name: Fludarabine Synonyms: 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE CAS: 21679-14-1 MF: C10H12FN5O4 MW: 285.23 EINECS: 244-525-5 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API Mol File: 21679-14-1.mol Fludarabine Chemical Properties mp 265-268°C storage temp. 2-8°C solubility DMF: 20 mg/mL, clear, faintly yellow Merck 13,4152 CAS DataBase Reference 21679-14-1(CAS DataBase Reference) Safety Information Risk Statements 23/24/25-36/37/38-39/23/24/25-39 Safety Statements 26-36/37-45 WGK Germany 3 RTECS AU6207000 F 10 Hazardous Substances Data 21679-14-1(Hazardous Substances Data) Fludarabine Usage Synthesis Chemical Properties White Solid Usage Used as an antineoplastic Usage A STAT-1 activation inhibita DNA synthesis inhibitor. Biological Activity Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) triggers apoptosis through increasing Bax decreasing Bid, XIAP survivin expression. Displays anticancer activity against hematological malignancies in vivo . Fludarabine Preparation Products Raw materials Raw materials Acetic anhydride-->Fluoroboric acid-->Boron trichloride -->2,4,5,6-TETRAAMINOPYRIMIDINE-->2,6-Diaminopurine-->DIACETAMIDE