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Home > Products >  Fludarabine

Fludarabine CAS NO.21679-14-1

  • Min.Order: 100 Gram
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Quick Details

  • ProName: Fludarabine
  • CasNo: 21679-14-1
  • Molecular Formula: C10H12FN5O4
  • Appearance: White Solid
  • Application: Irreversible muscarinic agonist .DNA s...
  • DeliveryTime: Within7-10 days after receipt of your ...
  • PackAge: As customer request
  • Port: Qingdao,China
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 98%
  • Storage: Store in a cool,dry place and keep awa...
  • Transportation: Common products:Sea/Air/Courier ...
  • LimitNum: 100 Gram
  • MW:: 285.23
  • EINECS:: 244-525-5
  • Mol File:: 21679-14-1.mol

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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

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  • Fludarabine Basic information
    Product Name: Fludarabine
    Synonyms: 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE
    CAS: 21679-14-1
    MF: C10H12FN5O4
    MW: 285.23
    EINECS: 244-525-5
    Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API
    Mol File: 21679-14-1.mol

     

    Fludarabine Chemical Properties
    mp 265-268°C
    storage temp. 2-8°C
    solubility DMF: 20 mg/mL, clear, faintly yellow
    Merck 13,4152
    CAS DataBase Reference 21679-14-1(CAS DataBase Reference)
     
    Safety Information
    Risk Statements 23/24/25-36/37/38-39/23/24/25-39
    Safety Statements 26-36/37-45
    WGK Germany 3
    RTECS AU6207000
    F 10
    Hazardous Substances Data 21679-14-1(Hazardous Substances Data)
    Fludarabine Usage Synthesis
    Chemical Properties White Solid
    Usage Used as an antineoplastic
    Usage A STAT-1 activation inhibita DNA synthesis inhibitor.
    Biological Activity Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) triggers apoptosis through increasing Bax decreasing Bid, XIAP survivin expression. Displays anticancer activity against hematological malignancies in vivo .
     
    Fludarabine Preparation Products Raw materials
    Raw materials Acetic anhydride-->Fluoroboric acid-->Boron trichloride -->2,4,5,6-TETRAAMINOPYRIMIDINE-->2,6-Diaminopurine-->DIACETAMIDE
     

 

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