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Prucalopride|5-HT4A and 5-HT4B receptor agonist CAS NO.179474-81-8
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- Min.Order: 10 Gram
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- Available Specifications:
99.5%(10-100)Gram99.5%(101-500)Gram
- Product Details
Keywords
- 179474-81-8 Prucalopride|5-HT4A and 5-HT4B receptor agonist
- China Prucalopride(179474-81-8) factory
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Quick Details
- ProName: Prucalopride|5-HT4A and 5-HT4B recepto...
- CasNo: 179474-81-8
- Molecular Formula: C18H26ClN3O3
- Appearance: white powder
- Application: used for research
- DeliveryTime: Within 3-7 days after receipt of your ...
- PackAge: As customer request
- Port: Qingdao,China
- ProductionCapacity: 100 Metric Ton/Day
- Purity: ≧99.5%
- Storage: Store in a cool,dry place and keep awa...
- Transportation: Common products:Sea/Air/Courier Dange...
- LimitNum: 10 Gram
- Moisture Content: 4.0~6.0%
- Impurity: ≦0.6%
- Single impurity: ≦0.1%
- Methanol: Methanol
Superiority
PRODUCT NAME :Prucalopride
CAS NUMBER: 179474-81-8
Other name:R 093877;R093877;Resolor;Unii-0A09iuw5tp;Prucalopride(R-93877)
Other name:R 093877;R093877;Resolor;Unii-0A09iuw5tp;Prucalopride(R-93877)
Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,
including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc
Details
Prucalopride
PRODUCT NAME :Prucalopride
STRUCTURE
CAS NUMBER: 179474-81-8
MOLECULAR FORMULA C18H26ClN3O3
MOLECULAR WEIGHT 367.874
BATCH NO. 201711002
STRUCTURE
CAS NUMBER: 179474-81-8
MOLECULAR FORMULA C18H26ClN3O3
MOLECULAR WEIGHT 367.874
BATCH NO. 201711002
Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,
including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc
Mete-analysis showed that the efficacy rate was significantly higher in prucalopride(179474-81-8)group （29.2%） than in the placebo group （12.6%, RR=2.37, 95% CI 2.02-2.79, P〈0.001）, while it was similar to that of PEG 3350＋electrolytes group. The incidence rates of headache, dizziness, diarrhea, abdominal pain, and nausea were higher in the prucalopride group than in the placebo group （P≤ 0.05）. There were no differences in the incidence of flatulence and prolonged Q T interval between the two groups （P〉0.05）. Conclusion Prucalopride is effective in the treatment of CC, with relatively milder and lower incidence of adverse reaction, and it could be a new choice for the treatment of CC.
Specification
Test Item Criteria Prescribe
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Characteristics White to off-white powder
Water 4.0~6.0%
Melting point 100~110
Single impurity ≦0.1%
Purity ≧99.5%
Solvent residue Methanol≦0.3%, Ethyl Alcohol≦0.5% ,THF≦0.072%
