- Product Details
Keywords
- AZD-9291
- 99%AZD-9291
- AZD-9291
Quick Details
- ProName: AZD-9291 CAS1421373-65-0
- CasNo: 1421373-65-0
- Molecular Formula: C28H33N7O2
- Appearance: white powder
- Application: AZD 9291 is an irreversible inhibitor ...
- DeliveryTime: Within7-10 days after receipt of your ...
- PackAge: As customer request
- Port: Qingdao,China
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Transportation: By Sea/Air/Courier
- LimitNum: 1 Gram
Superiority
Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.
Details
AZD-9291
CAS: | 1421373-65-0 |
MF: | C28H33N7O2 |
MW: | 499.61 |
Appearance: | White powder |
Assay: | 99% |
density: | 1.19±0.1 g/cm3(Predicted) |
Uses: | AZD-9291 (Osimertinib) is a oral, third generation, small-molecule epidermal growth factor receptor (EGFR) inhibitor and antineoplastic agent. In addition, it is a Cytochrome P450 3A inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor. It is used for the treatment of advanced non-small cell lung cancer (NSCLC) where mutant EGFR form (such as T790M) is often presented. Through suppressing the EGFR-mediated signalling, it cause cell death and inhibit tumour growth in related cancer cells. |